Leptin Receptor antibody (AA 501-600) (PE)

Catalog No. ABIN730313

The Rabbit Polyclonal anti-Leptin Receptor antibody has been validated for WB, FACS. It is suitable to detect Leptin Receptor in samples from Human, Mouse, Rat. There is 1 publication available.

Quick Overview for Leptin Receptor antibody (AA 501-600) (PE) (ABIN730313)

Target: Leptin Receptor (LEPR)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Leptin Receptor antibody is conjugated to PE

Application: Western Blotting (WB), Flow Cytometry (FACS)

Product Details anti-Leptin Receptor Antibody (PE)

Binding Specificity: AA 501-600

Cross-Reactivity: Human, Mouse, Rat

Predicted Reactivity: Dog,Cow,Sheep,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human of human Leptin receptor

Isotype: IgG

Application Details

Application Notes: FCM 1:20-100

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

References for anti-Leptin Receptor antibody (PE) (ABIN730313)

De Matteis, Grandoni, Scatà, Catizone, Reale, Crisà, Moioli: "Evaluation of leptin receptor expression on buffalo leukocytes." in: Veterinary immunology and immunopathology, Vol. 177, pp. 16-23, (2016) (PubMed).

Target Details for Leptin Receptor

Target: Leptin Receptor (LEPR)

Alternative Name: Leptin Receptor

Background:

Synonyms: OBR, OB-R, CD295, LEP-R, LEPRD, Leptin receptor, HuB219, OB receptor, LEPR, DB

Background: Receptor for obesity factor (leptin). On ligand binding, mediates signaling through JAK2/STAT3. Involved in the regulation of fat metabolism and, in a hematopoietic pathway, required for normal lymphopoiesis. May play a role in reproduction. Can also mediate the ERK/FOS signaling pathway (By similarity).

Gene ID: 3953

UniProt: P48357

Pathways: JAK-STAT Signaling, AMPK Signaling, Feeding Behaviour