Leptin Receptor antibody (PE-Cy5)

Catalog No. ABIN730315

This Rabbit Polyclonal antibody specifically detects Leptin Receptor in WB and FACS. It exhibits reactivity toward Human, Mouse, Rat, Pig, Dog and Cow.

Quick Overview for Leptin Receptor antibody (PE-Cy5) (ABIN730315)

Target: Leptin Receptor (LEPR)

Reactivity: Human, Mouse, Rat, Pig, Dog, Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Leptin Receptor antibody is conjugated to PE-Cy5

Application: Western Blotting (WB), Flow Cytometry (FACS)

Product Details anti-Leptin Receptor Antibody (PE-Cy5)

Cross-Reactivity: Human, Mouse, Rat

Predicted Reactivity: Dog,Cow,Sheep,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human of human Leptin receptor

Isotype: IgG

Application Details

Application Notes: FCM(1:100-500)
Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for Leptin Receptor

Target: Leptin Receptor (LEPR)

Alternative Name: Leptin receptor

Background:

Synonyms: OBR, OB-R, CD295, LEP-R, LEPRD, Leptin receptor, HuB219, OB receptor, LEPR, DB

Background: Receptor for obesity factor (leptin). On ligand binding, mediates signaling through JAK2/STAT3. Involved in the regulation of fat metabolism and, in a hematopoietic pathway, required for normal lymphopoiesis. May play a role in reproduction. Can also mediate the ERK/FOS signaling pathway (By similarity).

Molecular Weight: 132kDa

Gene ID: 3953

UniProt: P48357

Pathways: JAK-STAT Signaling, AMPK Signaling, Feeding Behaviour