GLP1R antibody (AA 101-200)

Catalog No. ABIN731333

The Rabbit Polyclonal anti-GLP1R antibody has been validated for WB, ELISA, IP, ICC, FACS, IHC (p), IHC (fro), IF (cc) and IF (p). It is suitable to detect GLP1R in samples from Human, Mouse and Rat. There are 2+ publications available.

Quick Overview for GLP1R antibody (AA 101-200) (ABIN731333)

Target: GLP1R (Glucagon-Like Peptide 1 Receptor (GLP1R))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GLP1R antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunoprecipitation (IP), Immunocytochemistry (ICC), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-GLP1R Antibody

Binding Specificity: AA 101-200

Cross-Reactivity: Human, Mouse, Rat

Predicted Reactivity: Dog

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from rat GLP-1R

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
IP(1-2 μg)
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-GLP1R antibody (ABIN731333)

Nagai, Doi, Nakashima, Irifuku, Sasaki, Ueno, Masaki: "Linagliptin Ameliorates Methylglyoxal-Induced Peritoneal Fibrosis in Mice." in: PLoS ONE, Vol. 11, Issue 8, pp. e0160993, (2016) (PubMed).

Zhou, Yang, Xin, Li, Guo, Hu, Zhou, Zhang, Zhang, Han, Chen: "Exendin-4 protects adipose-derived mesenchymal stem cells from apoptosis induced by hydrogen peroxide through the PI3K/Akt-Sfrp2 pathways." in: Free radical biology & medicine, Vol. 77, pp. 363-75, (2014) (PubMed).

Target Details for GLP1R

Target: GLP1R (Glucagon-Like Peptide 1 Receptor (GLP1R))

Alternative Name: GLP-1R

Background:

Synonyms: GLP-1R, GLP1Rc, Glucagon-like peptide 1 receptor, GLP-1 receptor, GLP-1-R, Glp1r, GLP1R_RAT

Background: This is a receptor for glucagon-like peptide 1. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.

Gene ID: 25051

UniProt: P32301

Pathways: Positive Regulation of Peptide Hormone Secretion, Hormone Transport, cAMP Metabolic Process, Feeding Behaviour