TIGIT antibody

Catalog No. ABIN7646823

The Mouse Monoclonal anti-TIGIT antibody (Clone D14) (ABIN7646823) specifically detects TIGIT in WB, IHC, ICC and IP. The antibody is reactive with Human samples.

Quick Overview for TIGIT antibody (ABIN7646823)

Target: TIGIT (T Cell Immunoreceptor with Ig and ITIM Domains (TIGIT))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This TIGIT antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunoprecipitation (IP)

Clone: D14

Product Details anti-TIGIT Antibody

Purpose: Monoclonal Antibody to T-Cell Immunoreceptor With Ig And ITIM Domains Protein (TIGIT)

Specificity: The antibody is a mouse monoclonal antibody raised against TIGIT. It has been selected for its ability to recognize TIGIT in immunohistochemical staining and western blotting.

Purification: Protein A + Protein G affinity chromatography

Immunogen: RPN056Hu01Recombinant TCell Immunoreceptor With Ig And ITIM Domains Protein (TIGIT)

Application Details

Application Notes: Western blotting: 0.01-2 μg/mL,Immunohistochemistry: 5-20 μg/mL,Immunocytochemistry: 5-20 μg/mL,Optimal working dilutions must be determined by end user.

Comment:

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium azide, 50 % glycerol.

Preservative: ProClin, Sodium azide

Precaution of Use: This product contains ProClin and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Target Details for TIGIT

Target: TIGIT (T Cell Immunoreceptor with Ig and ITIM Domains (TIGIT))

Alternative Name: TIGIT

Background: VSIG9, VSTM3, V-Set And Immunoglobulin Domain Containing 9, V-Set And Transmembrane Domain Containing 3

UniProt: Q495A1

Pathways: Cancer Immune Checkpoints