VEGFC antibody (AA 321-415) (HRP)

Catalog No. ABIN731732

The Rabbit Polyclonal anti-VEGFC antibody has been validated for WB, ELISA, IHC (p) and IHC (fro). It is suitable to detect VEGFC in samples from Human, Mouse and Rat.

Quick Overview for VEGFC antibody (AA 321-415) (HRP) (ABIN731732)

Target: VEGFC (Vascular Endothelial Growth Factor C (VEGFC))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This VEGFC antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-VEGFC Antibody (HRP)

Binding Specificity: AA 321-415

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from mouse VEGF-C

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for VEGFC

Target: VEGFC (Vascular Endothelial Growth Factor C (VEGFC))

Alternative Name: VEGF-C

Background:

Synonyms: VEGF-C, AW228853, Vascular endothelial growth factor C, Flt4 ligand, Flt4-L, Vascular endothelial growth factor-related protein, VRP, Vegfc

Background: Growth factor active in angiogenesis, and endothelial cell growth, stimulating their proliferation and migration and also has effects on the permeability of blood vessels. May function in angiogenesis of the venous and lymphatic vascular systems during embryogenesis, and also in the maintenance of differentiated lymphatic endothelium in adults. Binds and activates VEGFR-2 (KDR/FLK1) and VEGFR-3 (FLT4) receptors.

Gene ID: 22341

UniProt: P97953

Pathways: RTK Signaling, Signaling Events mediated by VEGFR1 and VEGFR2