DPP4 antibody (CF®740)

Catalog No. ABIN7653187

This Mouse Monoclonal antibody specifically detects DPP4 in . It exhibits reactivity toward Human and Rat.

Quick Overview for DPP4 antibody (CF®740) (ABIN7653187)

Target: DPP4 (Dipeptidyl-Peptidase 4 (DPP4))

Reactivity: Human, Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This DPP4 antibody is conjugated to CF®740

Application: Please inquire

Clone: DPP4-910

Product Details anti-DPP4 Antibody (CF®740)

Purpose: CD26(DPP4/910), CF740 conjugate

Characteristics: Recognizes a glycoprotein of 110 kDa, identified as CD26. It is an atypical serine protease belonging to the prolyl oligopeptidase family. It is expressed on lymphocyte cells and is upregulated during T-cell activation. CD26 is also expressed on activated B cells and natural killer cells and abundantly on epithelia. CD26 is implicated in a variety of biological functions including T-cell activation, cell adhesion with extracellular matrix such as fibronectin or collagens, and in HIV infection.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogen: Recombinant human DPP4 protein

Isotype: IgG2b, kappa

Application Details

Application Notes: For coating for ELISA, order Ab without BSA. Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody. Not recommended for FFPE. Optimal dilution and staining procedure for a specific application should be determined by user. Recommended starting concentrations for titration are 1-2 μg/mL for most applications, or 1 μg/million cells/100 μLfor flow cytometry. Does not react with pig or sheep, others not tested

Comment:

Positive Control: U-87 MG (Human glioblastoma astrocytoma), Ramos (Human Burkitt lymphoma, HEP-G2 cells, and lymphocytes. Lymph nodes and tonsils.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.1 mg/mL

Buffer: PBS, 0.1 % rBSA, 0.05 % azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Protect from light

Storage: 4 °C

Storage Comment:

Stable at room temperature or 37°C for 7 days.

Protect from light

Store at 2 to 8°C. Protect fluorescent conjugates from light

Expiry Date: 24 months

Target Details for DPP4

Target: DPP4 (Dipeptidyl-Peptidase 4 (DPP4))

Alternative Name: CD26

Background:

Synonyms: ADA-binding protein (ADABP), Adenosine deaminase complexing protein 2 (ADCP-2), Dipeptidyl peptidase 4, Dipeptidyl peptidase 4 soluble form, Dipeptidyl peptidase IV membrane form, Dipeptidyl peptidase IV soluble form, Dipeptidyl peptidase, intestinal, Dipeptidylpeptidase 4, Dipeptidylpeptidase IV, DPP4, DPPIV, Intestinal dipeptidyl peptidase, T-cell activation antigen CD26, TP103

Gene Symbol: DPP4

Tissue Expression: Epithelial cells

Molecular Weight: ~110 kDa

Gene ID: 1803

UniProt: P27487

Pathways: Peptide Hormone Metabolism, Regulation of Leukocyte Mediated Immunity