Recombinant JUP antibody (CF®647)

Catalog No. ABIN7655811

This anti-JUP antibody is a Mouse Monoclonal antibody detecting JUP in IF and FACS. Suitable for Human.

Quick Overview for Recombinant JUP antibody (CF®647) (ABIN7655811)

Target: JUP (Junction Plakoglobin (JUP))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This JUP antibody is conjugated to CF®647

Application: Immunofluorescence (IF), Flow Cytometry (FACS)

Clone: RCTNG-1664

Product Details anti-JUP Antibody (CF®647)

Purpose: Catenin, gamma (Cardiomyocyte Marker)(rCTNG/1664), CF647 conjugate

Characteristics: Gamma catenin, also known as JUP or junction plakoglobin, is a member of the catenin family. The catenins (alpha, beta, gamma, and delta) are ubiquitously expressed, cytoplasmic proteins that associate with E-cadherin at cellular junctions. Catenin/cadherin complexes play an important role in mediating cellular adhesion, including adherens junctions. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogen: Recombinant human gamma catenin protein

Isotype: IgG1, kappa

Application Details

Application Notes: ELISA: For coating, order Ab without BSA, Flow cytometry: 1-2 μg/million cells, Immunofluorescence: 1-2 μg/mL, Western blot 1-2 μg/mL, Optimal dilution for a specific application should be determined.. Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody

Comment:

Positive Control: A431, T47D or MCF-7 cells. Skin

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.1 mg/mL

Buffer: PBS, 0.1 % BSA, 0.05 % azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Protect from light

Storage: 4 °C

Storage Comment:

Stable at room temperature or 37°C for 7 days.

Protect from light

Store at 2 to 8°C. Protect fluorescent conjugates from light

Expiry Date: 24 months

Target Details for JUP

Target: JUP (Junction Plakoglobin (JUP))

Alternative Name: Gamma-catenin

Background:

Synonyms: Gamma catenin, JUP, Junction plakoglobin, Catenin gamma

Gene Symbol: JUP

Tissue Expression: Epithelial cells

Molecular Weight: 80-87 kDa

Gene ID: 3728

UniProt: P14923

Pathways: Cell-Cell Junction Organization, Maintenance of Protein Location