Nuclear Antigen antibody

Catalog No. ABIN7658078

The Mouse Monoclonal anti-Nuclear Antigen antibody is suitable to detect Nuclear Antigen in samples from Human, Mouse and Rat. It has been validated for IHC and IHC (fp).

Quick Overview for Nuclear Antigen antibody (ABIN7658078)

Target: Nuclear Antigen (IPO-38)

Reactivity: Human, Mouse, Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This Nuclear Antigen antibody is un-conjugated

Application: Immunohistochemistry (IHC), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Clone: IPO-38

Product Details anti-Nuclear Antigen Antibody

Purpose: IPO-38(IPO-38)

Characteristics: Recognizes a protein of 14-16 kDa, which is a novel nuclear antigen of proliferating cells. IPO-38 antigen is present in the nuclei of proliferating cells such as Hodgkin's disease and non-Hodgkin's lymphomas, different forms of leukemias, breast and colorectal carcinomas, and PHA-stimulated lymphocytes. It is not expressed in the cells of non-stimulated lymphocytes and granulocytes. IPO-38 may be a useful marker of cell proliferation during monitoring of tumor progression. This antibody is available purified with BSA/azide at 200 μg/mL, or BSA/azide-free at 1 mg/mL.

Immunogen: Spleen cells of a patient with hairy cell leukemia

Isotype: IgM, kappa

Application Details

Application Notes: Immunofluorescence 0.5-1 μg/mL. Flow Cytometry 0.5-1 μg/million cells/0.1 mL

Comment:

Positive Control: Raji and PHA-stimulated (>12 hours) human or mouse lymphocytes. Breast and colorectal carcinomas.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: PBS, 0.05 % BSA, 0.05 % azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment:

Stable at room temperature or 37°C for 7 days.

Store at 2 to 8°C. Protect fluorescent conjugates from light

Expiry Date: 24 months

Target Details for Nuclear Antigen

Target: Nuclear Antigen (IPO-38)

Alternative Name: IPO-38

Background:

Synonyms: Not Known

Tissue Expression: Proliferating cells

Molecular Weight: 14-16 kDa