Nuclear Antigen (IPO-38) antibody

Details for Product No. ABIN6297660
Antigen
Reactivity
Human, Mouse (Murine), Rat (Rattus)
26
19
17
Host
Mouse
27
Clonality
Monoclonal
Application
Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (IHC)
22
20
16
10
4
4
3
3
2
1
Options
Purpose Mouse anti-Human/Mouse/Rat IPO-38 Antibody (Proliferation Marker) [Sodium Azide Free]
Immunogen Spleen cells from a patient with hairy cell leukemia were used as the immunogen for the IPO-38 antibody.
Specificity Nuclear
Purification Spleen cells from a patient with hairy cell leukemia were used as the immunogen for the IPO-38 antibody.
Antigen
Alternative Name IPO38
Background

Target Description: Recognizes a protein of 14-16 kDa, which is a novel nuclear antigen of proliferating cells. IPO38 antigen is present in the nuclei of proliferating cells such as Hodgkin s disease and non-Hodgkin s lymphomas, different forms of leukemias, breast and colorectal carcinomas, and PHA-stimulated lymphocytes. It is not expressed in the cells of non-stimulated lymphocytes and granulocytes. IPO38 may be a useful marker of cell proliferation during monitoring of tumor progression.

Application Notes Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
Immunofluorescence: 0.5-1 μg/mL
Immunohistochemistry (FFPE): 0.5-1 μg/mL for 30 min at RT (1)
Prediluted format: incubate for 30 min at RT (2)
Restrictions For Research Use only
Buffer In 1X PBS, BSA free, sodium azide free
Preservative Azide free
Storage 4 °C,-20 °C
Storage Comment 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
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