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Nuclear Antigen antibody

This Mouse Monoclonal antibody specifically detects Nuclear Antigen in IHC and IHC (fp). It exhibits reactivity toward Human, Mouse and Rat.
Catalog No. ABIN7658080

Quick Overview for Nuclear Antigen antibody (ABIN7658080)

Target

See all Nuclear Antigen (IPO-38) Antibodies
Nuclear Antigen (IPO-38)

Reactivity

Human, Mouse, Rat

Host

  • 6
Mouse

Clonality

  • 6
Monoclonal

Conjugate

  • 6
This Nuclear Antigen antibody is un-conjugated

Application

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Immunohistochemistry (IHC), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Clone

IPO-38
  • Purpose

    IPO-38(IPO-38)

    Characteristics

    Recognizes a protein of 14-16 kDa, which is a novel nuclear antigen of proliferating cells. IPO-38 antigen is present in the nuclei of proliferating cells such as Hodgkin's disease and non-Hodgkin's lymphomas, different forms of leukemias, breast and colorectal carcinomas, and PHA-stimulated lymphocytes. It is not expressed in the cells of non-stimulated lymphocytes and granulocytes. IPO-38 may be a useful marker of cell proliferation during monitoring of tumor progression. This antibody is available purified with BSA/azide at 200 μg/mL, or BSA/azide-free at 1 mg/mL.

    Immunogen

    Spleen cells of a patient with hairy cell leukemia

    Isotype

    IgM, kappa
  • Application Notes

    Immunofluorescence 0.5-1 μg/mL. Flow Cytometry 0.5-1 μg/million cells/0.1 mL

    Comment

    Positive Control: Raji and PHA-stimulated (>12 hours) human or mouse lymphocytes. Breast and colorectal carcinomas.

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 mg/mL

    Buffer

    PBS, no BSA, no azide

    Preservative

    Without preservative

    Storage

    -20 °C

    Storage Comment

    Stable at room temperature or 37°C for 7 days.

    Store at -20 °C. Protect fluorescent conjugates from light

    Expiry Date

    24 months
  • Target

    Nuclear Antigen (IPO-38)

    Alternative Name

    IPO-38

    Background

    Synonyms: Not Known

    Tissue Expression: Proliferating cells

    Molecular Weight

    14-16 kDa
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