Nuclear Antigen antibody
Quick Overview for Nuclear Antigen antibody (ABIN7658080)
Target
See all Nuclear Antigen (IPO-38) AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Purpose
- IPO-38(IPO-38)
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Characteristics
- Recognizes a protein of 14-16 kDa, which is a novel nuclear antigen of proliferating cells. IPO-38 antigen is present in the nuclei of proliferating cells such as Hodgkin's disease and non-Hodgkin's lymphomas, different forms of leukemias, breast and colorectal carcinomas, and PHA-stimulated lymphocytes. It is not expressed in the cells of non-stimulated lymphocytes and granulocytes. IPO-38 may be a useful marker of cell proliferation during monitoring of tumor progression. This antibody is available purified with BSA/azide at 200 μg/mL, or BSA/azide-free at 1 mg/mL.
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Immunogen
- Spleen cells of a patient with hairy cell leukemia
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Isotype
- IgM, kappa
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Application Notes
- Immunofluorescence 0.5-1 μg/mL. Flow Cytometry 0.5-1 μg/million cells/0.1 mL
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Comment
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Positive Control: Raji and PHA-stimulated (>12 hours) human or mouse lymphocytes. Breast and colorectal carcinomas.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS, no BSA, no azide
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Preservative
- Without preservative
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Storage
- -20 °C
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Storage Comment
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Stable at room temperature or 37°C for 7 days.
Store at -20 °C. Protect fluorescent conjugates from light
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Expiry Date
- 24 months
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- Nuclear Antigen (IPO-38)
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Alternative Name
- IPO-38
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Background
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Synonyms: Not Known
Tissue Expression: Proliferating cells
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Molecular Weight
- 14-16 kDa
Target
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