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Nuclear Antigen antibody

This Mouse Monoclonal antibody specifically detects Nuclear Antigen in IHC and IHC (fp). It exhibits reactivity toward Human, Mouse and Rat.
Catalog No. ABIN7658080
$566.15
Plus shipping costs $50.00
50 μL
Shipping to: United States
Delivery in 13 to 22 Business Days

Quick Overview for Nuclear Antigen antibody (ABIN7658080)

Target

See all Nuclear Antigen (IPO-38) Antibodies
Nuclear Antigen (IPO-38)

Reactivity

Human, Mouse, Rat

Host

  • 6
Mouse

Clonality

  • 6
Monoclonal

Conjugate

  • 6
This Nuclear Antigen antibody is un-conjugated

Application

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Immunohistochemistry (IHC), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Clone

IPO-38
  • Purpose

    IPO-38(IPO-38)

    Characteristics

    Recognizes a protein of 14-16 kDa, which is a novel nuclear antigen of proliferating cells. IPO-38 antigen is present in the nuclei of proliferating cells such as Hodgkin's disease and non-Hodgkin's lymphomas, different forms of leukemias, breast and colorectal carcinomas, and PHA-stimulated lymphocytes. It is not expressed in the cells of non-stimulated lymphocytes and granulocytes. IPO-38 may be a useful marker of cell proliferation during monitoring of tumor progression. This antibody is available purified with BSA/azide at 200 μg/mL, or BSA/azide-free at 1 mg/mL.

    Immunogen

    Spleen cells of a patient with hairy cell leukemia

    Isotype

    IgM, kappa
  • Application Notes

    Immunofluorescence 0.5-1 μg/mL. Flow Cytometry 0.5-1 μg/million cells/0.1 mL

    Comment

    Positive Control: Raji and PHA-stimulated (>12 hours) human or mouse lymphocytes. Breast and colorectal carcinomas.

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 mg/mL

    Buffer

    PBS, no BSA, no azide

    Preservative

    Without preservative

    Storage

    -20 °C

    Storage Comment

    Stable at room temperature or 37°C for 7 days.

    Store at -20 °C. Protect fluorescent conjugates from light

    Expiry Date

    24 months
  • Target

    Nuclear Antigen (IPO-38)

    Alternative Name

    IPO-38

    Background

    Synonyms: Not Known

    Tissue Expression: Proliferating cells

    Molecular Weight

    14-16 kDa
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