SELPLG antibody

Catalog No. ABIN7659765

This anti-SELPLG antibody is a Mouse Monoclonal antibody detecting SELPLG in . Suitable for Human.

Quick Overview for SELPLG antibody (ABIN7659765)

Target: SELPLG (Selectin P Ligand (SELPLG))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This SELPLG antibody is un-conjugated

Application: Please inquire

Clone: PSGL1-1567

Product Details anti-SELPLG Antibody

Purpose: CD162 (Selectin P Ligand)(PSGL1/1567)

Characteristics: CD162 glycoprotein functions as a high affinity counter-receptor for the cell adhesion molecules P-, E- and L- selectin expressed on myeloid cells and stimulated T lymphocytes. As such, this protein plays a critical role in leukocyte trafficking during inflammation by tethering of leukocytes to activated platelets or endothelia expressing selectins. This protein requires two post-translational modifications, tyrosine sulfation and the addition of the sialyl Lewis x tetrasaccharide (sLex) to its O-linked glycans, for its high-affinity binding activity. Aberrant expression of this gene and polymorphisms in this gene are associated with defects in the innate and adaptive immune response. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogen: Recombinant human SELPLG (CD162) protein

Isotype: IgM, kappa

Application Details

Application Notes: For coating for ELISA, order Ab without BSA. Optimal dilution and staining procedure for a specific application should be determined by user. Recommended starting concentrations for titration are 1-2 μg/mL for most applications, or 1 μg/million cells/100 μLfor flow cytometry

Comment:

Positive Control: Jurkat cells. Tonsil.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, no BSA, no azide

Preservative: Without preservative

Storage: -20 °C

Storage Comment:

Stable at room temperature or 37°C for 7 days.

Store at -20 °C. Protect fluorescent conjugates from light

Expiry Date: 24 months

Target Details for SELPLG

Target: SELPLG (Selectin P Ligand (SELPLG))

Alternative Name: CD162

Background:

Synonyms: CD162, CLA, Cutaneous lymphocyte associated antigen, P-selectin glycoprotein ligand 1, PSGL1, Selectin P ligand, SELPLG

Gene Symbol: SELPLG

Tissue Expression: Myeloid cells|T-cells

Molecular Weight: 43-120 kDa

Gene ID: 6404

UniProt: Q14242