UPK1A antibody (AA 114-173) (CF®405S)

Catalog No. ABIN7661613

This anti-UPK1A antibody is a Mouse Monoclonal antibody detecting UPK1A in IHC and IHC (fp). Suitable for Human.

Quick Overview for UPK1A antibody (AA 114-173) (CF®405S) (ABIN7661613)

Target: UPK1A (Uroplakin 1a (UPK1A))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This UPK1A antibody is conjugated to CF®405S

Application: Immunohistochemistry (IHC), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Clone: UPK1A-2921

Product Details anti-UPK1A Antibody (CF®405S)

Binding Specificity: AA 114-173

Purpose: Uroplakin 1A (Urothelial Differentiation Marker)(UPK1A/2921), CF405S conjugate

Characteristics: The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is found in the asymmetrical unit membrane (AUM) where it can complex with other transmembrane 4 superfamily proteins. It may play a role in normal bladder epithelial physiology, possibly in regulating membrane permeability of superficial umbrella cells or in stabilizing the apical membrane through AUM/cytoskeletal interactions. The protein may also play a role in tumor suppression. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogen: Recombinant fragment (around aa 114-173) of human Uroplakin 1A (UPK1A) protein

Isotype: IgG2b, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

Positive Control: Urinary Bladder.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.1 mg/mL

Buffer: PBS, 0.1 % BSA, 0.05 % azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Protect from light

Storage: 4 °C

Storage Comment:

Stable at room temperature or 37°C for 7 days.

Protect from light

Store at 2 to 8°C. Protect fluorescent conjugates from light

Expiry Date: 24 months

Target Details for UPK1A

Target: UPK1A (Uroplakin 1a (UPK1A))

Alternative Name: Uroplakin 1A

Background:

Synonyms: UP1A, UPIA, UPKA, TSPAN21

Gene Symbol: UPK1A

Molecular Weight: 29 kDa

Gene ID: 11045

UniProt: O00322