Calnexin antibody (AA 501-592) (Cy7)
Quick Overview for Calnexin antibody (AA 501-592) (Cy7) (ABIN733079)
Target
See all Calnexin (CANX) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 501-592
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Cross-Reactivity
- Mouse, Rat
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Predicted Reactivity
- Human,Cow,Horse,Chicken,Rabbit
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Purification
- Purified by Protein A.
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Immunogen
- KLH conjugated synthetic peptide derived from human CANX
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Isotype
- IgG
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Application Notes
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FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 μg/μL
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Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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Preservative
- ProClin
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Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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Expiry Date
- 12 months
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- Calnexin (CANX)
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Alternative Name
- Canx/Calnexin
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Background
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Synonyms: CNX, P90, IP90, Calnexin, Major histocompatibility complex class I antigen-binding protein p88, CANX
Background: Calcium-binding protein that interacts with newly synthesized glycoproteins in the endoplasmic reticulum. It may act in assisting protein assembly and/or in the retention within the ER of unassembled protein subunits. It seems to play a major role in the quality control apparatus of the ER by the retention of incorrectly folded proteins. Associated with partial T-cell antigen receptor complexes that escape the ER of immature thymocytes, it may function as a signaling complex regulating thymocyte maturation. Additionally it may play a role in receptor-mediated endocytosis at the synapse.
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Gene ID
- 821
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UniProt
- P27824
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Pathways
- MAPK Signaling, Thyroid Hormone Synthesis
Target
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