HMGB1 antibody (AA 1-90) (APC)

Catalog No. ABIN7666853

This Mouse Monoclonal antibody specifically detects HMGB1 in WB, IF and FACS. It exhibits reactivity toward Human.

Quick Overview for HMGB1 antibody (AA 1-90) (APC) (ABIN7666853)

Target: HMGB1 (High Mobility Group Box 1 (HMGB1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This HMGB1 antibody is conjugated to APC

Application: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)

Clone: 2F6

Product Details anti-HMGB1 Antibody (APC)

Binding Specificity: AA 1-90

Purpose: APC conjugated mouse monoclonal antibody raised against a partial recombinant HMGB1.

Sequence: MGKGDPKKPR GKMSSYAFFV QTCREEHKKK HPDASVNFSE FSKKCSERWK TMSAKEKGKF EDMAKADKAR YEREMKTYIP PKGETKKKFK

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: HMGB1 (NP_002119, 1 a.a. ~ 90 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG2a kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Storage: 4 °C

Storage Comment: Store at 4°C.

Target Details for HMGB1

Target: HMGB1 (High Mobility Group Box 1 (HMGB1))

Alternative Name: HMGB1

Background:

gene_description: high-mobility group box 1

gene_alias: DKFZp686A04236|HMG1|HMG3|SBP-1

Gene ID: 3146

NCBI Accession: NM_002128

Pathways: p53 Signaling, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Toll-Like Receptors Cascades, Smooth Muscle Cell Migration, Inflammasome