Progesterone Receptor antibody (AA 1-110) (APC)

Catalog No. ABIN7667006

This Mouse Monoclonal antibody specifically detects Progesterone Receptor in WB, IF and FACS. It exhibits reactivity toward Human.

Quick Overview for Progesterone Receptor antibody (AA 1-110) (APC) (ABIN7667006)

Target: Progesterone Receptor (PGR)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Progesterone Receptor antibody is conjugated to APC

Application: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)

Clone: 2C2

Product Details anti-Progesterone Receptor Antibody (APC)

Binding Specificity: AA 1-110

Purpose: APC conjugated mouse monoclonal antibody raised against a partial recombinant PGR. This PGR gene uses two distinct promoters and translation start sites in the first exon to produce two isoforms, A and B. The two isoforms are identical except for the additional 165 amino acids found in the N-terminus of isoform B. Our immunogen corresponds to the specific region of isoform B, thus this antibody is a PGR isofrom B specific antibody.

Sequence: MTELKAKGPR APHVAGGPPS PEVGSPLLCR PAAGPFPGSQ TSDTLPEVSA IPISLDGLLF PRPCQGQDPS DEKTQDQQSL SDVEGAYSRA EATRGAGGSS SSPPEKDSGL

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: PGR (NP_000917, 1 a.a. ~ 110 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG1 kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Storage: 4 °C

Storage Comment: Store at 4°C.

Target Details for Progesterone Receptor

Target: Progesterone Receptor (PGR)

Alternative Name: PGR

Background:

gene_description: progesterone receptor

gene_alias: NR3C3|PR

Gene ID: 5241

NCBI Accession: NM_000926

Pathways: Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Smooth Muscle Cell Migration