CD44 antibody

Catalog No. ABIN8063653

This Mouse Monoclonal antibody specifically detects CD44 in FACS. It exhibits reactivity toward Human.

Quick Overview for CD44 antibody (ABIN8063653)

Target: CD44

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD44 antibody is un-conjugated

Application: Flow Cytometry (FACS)

Clone: P2A1

Product Details anti-CD44 Antibody

Purpose: Purified Anti-Human CD44 Antibody[P2A1]

Isotype: IgG2a, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: ≥ 1 mg/mL

Buffer: Phosphate buffered solution, pH 7.2, containing 0.05 % proclin 300.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: avoid freeze / thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.

Expiry Date: 12 months

Target Details for CD44

Target: CD44

Alternative Name: CD44

Background: CDW,MIC,CSPG,Phagocytic glycoprotein,MDU,Pgp,CDW44,CSPG8,ECMR-III,HCELL,HUTCH-I,IN,LHR,MC56,MDU2,MDU3,MIC4,Pgp1,CD44,CD44 antigen,Epican,PGP-1,PGP-I,Phagocytic glycoprotein 1,Phagocytic glycoprotein I,H-CAM,CD44v, Pgp-1, EMCR III, CD44s,BA-1,CD 44,CD44 Molecule,CD44 Molecule (Indian blood group),CD44v9,Cell surface glycoprotein CD44,chondroitin sulfate proteoglycan 8,Extracellular matrix receptor III,GP90 lymphocyte homing/adhesion receptor,hematopoietic cell E- and L-selectin ligand,Heparan sulfate proteoglycan,Hermes antigen,homing function and Indian blood group system,HSA,HUTCH1,Hyaluronate receptor,INLU-related p80 Glycoprotein,MGC10468,MUTCH1,Soluble CD44,The protein encoded by this gene is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined. Alternative splicing is the basis for the structural and functional diversity of this protein, and may be related to tumor metastasis.

UniProt: P16070

Pathways: Glycosaminoglycan Metabolic Process, Autophagy, Negative Regulation of intrinsic apoptotic Signaling