CD80 antibody

Catalog No. ABIN7670033

This anti-CD80 antibody is a Mouse Monoclonal antibody detecting CD80 in FACS. Suitable for Human.

Quick Overview for CD80 antibody (ABIN7670033)

Target: CD80

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD80 antibody is un-conjugated

Application: Flow Cytometry (FACS)

Clone: 2F4

Product Details anti-CD80 Antibody

Purpose: Purified Anti-Human CD80 Antibody[2F4]

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: ≥ 1 mg/mL

Buffer: Phosphate buffered solution, pH 7.2, containing 0.05 % proclin 300.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: avoid freeze / thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.

Expiry Date: 12 months

Target Details for CD80

Target: CD80

Alternative Name: CD80

Background: LAB,CTLA-4 counter-receptor B,T-lymphocyte activation antigen CD,B7,B7-1,B7.1,BB1,CD28LG,CD28LG1,LAB7,CD80,CD28LGB7-1 antigen,T-lymphocyte activation antigen CD80,Activation B7-1 antigen,CTLA-4 counter-receptor B7.1, B7-1, BB1,B lymphocyte activation antigen B7,B7-1 antigen,B7-1 antigen),CD28 antigen ligand 1,CD80 antigen,CD80 antigen (CD28 antigen ligand 1,CD80 Molecule,Costimulatory factor CD80,costimulatory molecule variant IgV-CD80,B7-1 and B7-2, together with their receptors CD28 and CTLA-4, constitute one of the dominant co-stimulatory pathways that regulate T- and B-cell responses. Although both CTLA-4 and CD28 can bind to the same ligands, CTLA-4 binds to B7-1 and B7-2 with a 20-100 fold higher affinity than CD28 and is involved in the down-regulation of the immune response. B7-1 is expressed on activated B cells, activated T cells, and macrophages.

UniProt: P33681

Pathways: TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints