IL2 Receptor beta antibody

Catalog No. ABIN7670092

The Mouse Monoclonal anti-IL2 Receptor beta antibody is suitable to detect IL2 Receptor beta in samples from Human. It has been validated for FACS.

Quick Overview for IL2 Receptor beta antibody (ABIN7670092)

Target: IL2 Receptor beta (IL2RB) (Interleukin 2 Receptor, beta (IL2RB))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This IL2 Receptor beta antibody is un-conjugated

Application: Flow Cytometry (FACS)

Clone: TU27

Product Details anti-IL2 Receptor beta Antibody

Purpose: Purified Anti-Human CD122 Antibody[TU27]

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: ≥ 1 mg/mL

Buffer: Phosphate buffered solution, pH 7.2, containing 0.05 % proclin 300.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: avoid freeze / thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.

Expiry Date: 12 months

Target Details for IL2 Receptor beta

Target: IL2 Receptor beta (IL2RB) (Interleukin 2 Receptor, beta (IL2RB))

Alternative Name: CD122

Background: P70;IL2RB;CD122;IL15RB;P70-75;IL-2Rβ;p75;IL-2RB;Interleukin-2 receptor subunit beta;IL-2 receptor subunit beta;IL-2R subunit beta;High affinity IL-2 receptor subunit beta;Interleukin-15 receptor subunit beta;p70-75 (p75);IL-2RβCD122 antigen;High affinity IL 2 receptor beta subunit;High affinity IL 2 receptor subunit beta;IL2 receptor;Interleukin 2 receptor beta;interleukin 2 receptor subunit beta;P70 75;P7075,Functional IL-2 receptors can exist in two affinity states on cell surfaces, the high affinity complex consisting of heterotrimers of the alpha, beta, and gamma chains and the intermediate affinity complex comprising heterodimers of the beta and gamma chains. Individual beta chains and alpha chains exhibit low affinity IL-2 binding, and the gamma chain alone does not bind IL-2. In addition to their involvement in IL-2 mediated signal transduction, both the beta chain and gamma chain have been shown to be required for IL-15 mediated signaling. IL-2 R beta is a member of the cytokine receptor superfamily.

UniProt: P14784

Pathways: JAK-STAT Signaling, Growth Factor Binding