IL-4 antibody

Catalog No. ABIN7670095

The Mouse Monoclonal anti-IL-4 antibody is suitable to detect IL-4 in samples from Rat. It has been validated for FACS.

Quick Overview for IL-4 antibody (ABIN7670095)

Target: IL-4 (IL4) (Interleukin 4 (IL4))

Reactivity: Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This IL-4 antibody is un-conjugated

Application: Flow Cytometry (FACS)

Clone: 5B3

Product Details anti-IL-4 Antibody

Purpose: Purified Anti-Rat IL4 Antibody[5B3]

Isotype: IgG2a, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: ≥ 1 mg/mL

Buffer: Phosphate buffered solution, pH 7.2, containing 0.05 % proclin 300.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: avoid freeze / thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.

Expiry Date: 12 months

Target Details for IL-4

Target: IL-4 (IL4) (Interleukin 4 (IL4))

Alternative Name: IL4

Background: Interleukin,B-cell growth factor,B-cell stimulatory factor,Lymphocyte stimulatory factor,BCGF1,B-cell IGG differentiation factor,B-cell stimulatory factor 1,BCGF-1,Binetrakin,BSF1,Interleukin-4,Lymphocyte stimulatory factor 1,Pitrakinra,Il4,BSF-1,Lymphocy,Il 4,B-cell growth factor 1,Il-4,IL4, BCGF-1, BCGF1, BSF-1, BSF1,IL-4 is a pleiotropic cytokine that is produced by activated T cells, mast cells and basophils. IL-4 elicits many different biological responses, but has two dominant functions. The first is regulating differentiation of naive CD4+ T cell to the Th2 type. Th2 cells produce IL-4, IL-5, IL-10 and IL-13, which tend to favor a humoral immune response while suppressing a cell-mediated immune response controlled by Th1 cells. The second is regulating IgE and IgG1 production by B cells.

UniProt: P20096

Pathways: JAK-STAT Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Proton Transport, Activated T Cell Proliferation