Leptin Receptor antibody

Catalog No. ABIN7670679

The Rabbit Polyclonal anti-Leptin Receptor antibody has been validated for ELISA. It is suitable to detect Leptin Receptor in samples from Mouse.

Quick Overview for Leptin Receptor antibody (ABIN7670679)

Target: Leptin Receptor (LEPR)

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Leptin Receptor antibody is un-conjugated

Application: ELISA

Product Details anti-Leptin Receptor Antibody

Purpose: Leptin R Polyclonal Antibody(Capture/Detector)

Purification: Antigen Affinity Purification

Immunogen: Recombinant Mouse Leptin R protein expressed by Mammalian

Isotype: IgG

Application Details

Application Notes: ELISA Capture 2-8 μg/mL,ELISA Detector 0.1-0.4 μg/mL

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Sterile PBS , pH 7.4

Preservative: Without preservative

Handling Advice: Avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C Valid for 1 month or -20°C Valid for 12 months

Expiry Date: 12 months

Target Details for Leptin Receptor

Target: Leptin Receptor (LEPR)

Alternative Name: Leptin R

Background: CD295,LEP-R,LR,LEPRD,OB-R,OBR,The protein encoded by this gene belongs to the gp130 family of cytokine receptors that are known to stimulate gene transcription via activation of cytosolic STAT proteins. This protein is a receptor for leptin (an adipocyte-specific hormone that regulates body weight), and is involved in the regulation of fat metabolism, as well as in a novel hematopoietic pathway that is required for normal lymphopoiesis. Mutations in this gene have been associated with obesity and pituitary dysfunction. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. It is noteworthy that this gene and LEPROT gene (GeneID:54741) share the same promoter and the first 2 exons, however, encode distinct proteins (PMID:9207021).

UniProt: P48356

Pathways: JAK-STAT Signaling, AMPK Signaling, Feeding Behaviour