Integrin Alpha2b antibody (PE-Cy5)

Catalog No. ABIN7673824

This anti-Integrin Alpha2b antibody is a Mouse Monoclonal antibody detecting Integrin Alpha2b in FACS. Suitable for Human.

Quick Overview for Integrin Alpha2b antibody (PE-Cy5) (ABIN7673824)

Target: Integrin Alpha2b (CD41)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Integrin Alpha2b antibody is conjugated to PE-Cy5

Application: Flow Cytometry (FACS)

Clone: HIP8

Product Details anti-Integrin Alpha2b Antibody (PE-Cy5)

Purpose: PE-Cy5 Anti-Human CD41 Antibody

Purification: 0

Purity: 0

Isotype: IgG1, kappa

Application Details

Application Notes: Volume per test: 5μL. Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 μL of antibody per test (million cells in 100 μL staining volume or per 100 μL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0. 1 % sodium azide, 1 % BSA, pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: 4 °C

Storage Comment: 2-8°C for 12 months (Avoid repeated freeze / thaw cycles.)

Expiry Date: 12 months

Target Details for Integrin Alpha2b

Target: Integrin Alpha2b (CD41)

Alternative Name: CD41

Background:

Synonyms: ITGAB|CD41|GP2B|GPIIb|GPalpha Iib|ITGA2B|Integrin alpha-Iib|Platelet membrane glycoprotein Iib

Background: CD41 is a 125/25 kD α subunit of the gpIIb/IIIa (CD41/CD61) complex. CD41 is a heterodimer composed of a heavy chain (gpIIbα) and light chain (gpIIbβ) linked by a single disulfide bond. It is a member of the integrin family primarily expressed on platelets and megakaryocytes. CD41 has been reported to be involved with platelet aggregation and platelet attachment to the ECM. CD41/CD61 complex acts as the receptor for fibrinogen, fibronectin, Von Willebrand factor and thrombin.

Molecular Weight: 0

Gene ID: 3674

UniProt: P08514

Pathways: Integrin Complex