Recombinant MTOR antibody (pSer2448) (Biotin)

Catalog No. ABIN7765684

The Rabbit Monoclonal anti-MTOR antibody is suitable to detect MTOR in samples from Human, Mouse, Rat and Pig. It has been validated for WB, IHC, IF and ICC.

Quick Overview for Recombinant MTOR antibody (pSer2448) (Biotin) (ABIN7765684)

Target: MTOR (mTOR) (Mechanistic Target of Rapamycin (serine/threonine Kinase) (mTOR))

Antibody Type: Recombinant Antibody

Reactivity: Human, Mouse, Rat, Pig

Host: Rabbit

Clonality: Monoclonal

Conjugate: This MTOR antibody is conjugated to Biotin

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Clone: SR1454

Product Details anti-MTOR Antibody (Biotin)

Binding Specificity: pSer2448

Purpose: Conjugated mTOR (Phospho-Ser2448) Rabbit mAb

Specificity: Phospho-mTOR (S2448) Antibody detects endogenous levels of total Phospho-mTOR (S2448)

Purification: Affinity-chromatography

Immunogen: A synthesized peptide derived from human Phospho-mTOR (S2448)

Application Details

Application Notes: working with enzyme-conjugated streptavidin, most applications: 1: 50 - 1: 1,000

Restrictions: For Research Use only

Handling

Buffer: Liquid in PBS, 0.5 % BSA, 40 % Glycerol, 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Protect from light!

Storage: 4 °C

Storage Comment: Store at 4°C in dark for 6 months

Target Details for MTOR

Target: MTOR (mTOR) (Mechanistic Target of Rapamycin (serine/threonine Kinase) (mTOR))

Alternative Name: mTOR

Background: FRAP, FRAP1, FRAP2, RAFT1, Rapamycin target protein, kinase mTOR,

Molecular Weight: Predicted band size: 289 kDa

UniProt: P42345

Pathways: PI3K-Akt Signaling, RTK Signaling, AMPK Signaling, Interferon-gamma Pathway, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Actin Filament Polymerization, Regulation of Muscle Cell Differentiation, Regulation of Cell Size, Skeletal Muscle Fiber Development, Regulation of Carbohydrate Metabolic Process, Autophagy, CXCR4-mediated Signaling Events, BCR Signaling, Warburg Effect