GRIA4 antibody (AA 501-600)

Catalog No. ABIN734618

The Rabbit Polyclonal anti-GRIA4 antibody is suitable to detect GRIA4 in samples from Human. It has been validated for WB, IHC (p), IF (cc), IF (p) and IHC (fro).

Quick Overview for GRIA4 antibody (AA 501-600) (ABIN734618)

Target: GRIA4 (Glutamate Receptor, Ionotropic, AMPA 4 (GRIA4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GRIA4 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-GRIA4 Antibody

Binding Specificity: AA 501-600

Purpose: GLUR4 Polyclonal Antibody

Cross-Reactivity: Human, Mouse

Predicted Reactivity: Rat,Dog,Cow,Pig

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GLUR4

Isotype: IgG

Application Details

Application Notes: WB(1:300-5000),

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for GRIA4

Target: GRIA4 (Glutamate Receptor, Ionotropic, AMPA 4 (GRIA4))

Alternative Name: GLUR4

Background:

Synonyms: AMPA 4, AMPA selective glutamate receptor 4, GluR 4, GluR D, GLUR4, GLUR4C, GLURD, Glutamate receptor 4, Glutamate receptor ionotrophic AMPA 4, GRIA 4, GRIA4, GRIA4_HUMAN.

Background: Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes composed of multiple subunits, arranged to form ligand-gated ion channels. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. The subunit encoded by this gene belongs to a family of AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate)-sensitive glutamate receptors, and is subject to RNA editing (AGA->GGA, R->G). Alternative splicing of this gene results in transcript variants encoding different isoforms, which may vary in their signal transduction properties.

Gene ID: 2893

Pathways: PI3K-Akt Signaling