PEG3 antibody (AA 1501-1588)

Catalog No. ABIN735653

There are 2+ publications for this product available. The Rabbit Polyclonal anti-PEG3 antibody is suitable to detect PEG3 in samples from Human. It has been validated for WB, IF (cc), IF (p), IHC (p) and IHC (fro).

Quick Overview for PEG3 antibody (AA 1501-1588) (ABIN735653)

Target: PEG3 (Paternally Expressed 3 (PEG3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PEG3 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-PEG3 Antibody

Binding Specificity: AA 1501-1588

Purpose: PEG3 Polyclonal Antibody

Cross-Reactivity: Human, Mouse, Rat

Predicted Reactivity: Cow,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human PEG3

Isotype: IgG

Application Details

Application Notes: WB(1:300-5000),

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-PEG3 antibody (ABIN735653)

Yao, Norris, Mason, Strickland: "Laminin regulates PDGFRβ(+) cell stemness and muscle development." in: Nature communications, Vol. 7, pp. 11415, (2016) (PubMed).

Ge, Liang, Luo, Wei, Han, Schatten, Sun, Zhang: "Diabetic uterus environment may play a key role in alterations of DNA methylation of several imprinted genes at mid-gestation in mice." in: Reproductive biology and endocrinology : RB&E, Vol. 11, Issue 1, pp. 119, (2014) (PubMed).

Target Details for PEG3

Target: PEG3 (Paternally Expressed 3 (PEG3))

Alternative Name: PEG3

Background:

Synonyms: PW1, ZNF94, ZSCAN24, ZKSCAN22, Paternally-expressed gene 3 protein, Zinc finger and SCAN domain-containing protein 24, PEG3, KIAA287

Background: Induces apoptosis in cooperation with SIAH1A. Acts as a mediator between p53/TP53 and BAX in a neuronal death pathway that is activated by DNA damage. Acts synergistically with TRAF2 and inhibits TNF induced apoptosis through activation of NF-kappa-B (By similarity). Possesses a tumor suppressing activity in glioma cells.

Gene ID: 5178

UniProt: Q9GZU2