Peroxiredoxin 3 antibody (AA 161-256)

Catalog No. ABIN735713

The Rabbit Polyclonal anti-Peroxiredoxin 3 antibody has been validated for WB, ELISA, IHC (p), IF (cc), IF (p) and IHC (fro). It is suitable to detect Peroxiredoxin 3 in samples from Human and Rat. There is 1 publication available.

Quick Overview for Peroxiredoxin 3 antibody (AA 161-256) (ABIN735713)

Target: Peroxiredoxin 3 (PRDX3)

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Peroxiredoxin 3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-Peroxiredoxin 3 Antibody

Binding Specificity: AA 161-256

Cross-Reactivity: Human, Rat

Predicted Reactivity: Mouse,Dog,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human PRDX3

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-Peroxiredoxin 3 antibody (ABIN735713)

Gao, Liu, Chen, Lv, Wu, Mi, Wang: "Comparative study of Hsp27, GSK3?, Wnt1 and PRDX3 in Hirschsprung's disease." in: International journal of experimental pathology, Vol. 95, Issue 3, pp. 229-37, (2014) (PubMed).

Target Details for Peroxiredoxin 3

Target: Peroxiredoxin 3 (PRDX3)

Alternative Name: PRDX3/peroxiredoxin 3

Background:

Synonyms: AOP1, MER5, AOP-1, SP-22, HBC189, PRO1748, prx-III, Thioredoxin-dependent peroxide reductase, mitochondrial, Antioxidant protein 1, Peroxiredoxin III, Peroxiredoxin-3, Protein MER5 homolog, PRDX3

Background: Involved in redox regulation of the cell. Protects radical-sensitive enzymes from oxidative damage by a radical-generating system. Acts synergistically with MAP3K13 to regulate the activation of NF-kappa-B in the cytosol.

Gene ID: 10935

UniProt: P30048

Pathways: Ribonucleoside Biosynthetic Process, Methionine Biosynthetic Process