Recombinant IL-13 antibody (PE)

Catalog No. ABIN7795029

The Rabbit Chimeric anti-IL-13 antibody has been validated for FACS and Func. It is suitable to detect IL-13 in samples from Human.

Quick Overview for Recombinant IL-13 antibody (PE) (ABIN7795029)

Target: IL-13 (IL13) (Interleukin 13 (IL13))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Chimeric

Conjugate: This IL-13 antibody is conjugated to PE

Application: Flow Cytometry (FACS), Functional Studies (Func)

Clone: 1A1

Product Details anti-IL-13 Antibody (PE)

Purpose: PE-conjugated Anti-IL13 antibody(1A1), IgG1 Chimeric mAb

Purification: Purified from cell culture supernatant by affinity chromatography

Isotype: IgG1

Application Details

Application Notes: FACS 1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid,PBS with 0.05 % Proclin300, 1 % BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store at 2°C-8°C for 6 months

Target Details for IL-13

Target: IL-13 (IL13) (Interleukin 13 (IL13))

Alternative Name: IL13

Background: IL-13,NC30,This gene encodes an immunoregulatory cytokine produced primarily by activated Th2 cells. This cytokine is involved in several stages of B-cell maturation and differentiation. It up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. This cytokine down-regulates macrophage activity, thereby inhibits the production of pro-inflammatory cytokines and chemokines. This cytokine is found to be critical to the pathogenesis of allergen-induced asthma but operates through mechanisms independent of IgE and eosinophils. This gene, IL3, IL5, IL4, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL4. [provided by RefSeq, Jul 2008]

UniProt: P35225

Pathways: JAK-STAT Signaling, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Proton Transport