Recombinant TIGIT antibody

Catalog No. ABIN7795336

The Mouse Monoclonal anti-TIGIT antibody (Clone 1F4) (ABIN7795336) specifically detects TIGIT in WB, IHC, FACS, ELISA, ICC and in vivo. The antibody is reactive with Mouse samples.

Quick Overview for Recombinant TIGIT antibody (ABIN7795336)

Target: TIGIT (T Cell Immunoreceptor with Ig and ITIM Domains (TIGIT))

Antibody Type: Recombinant Antibody

Reactivity: Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This TIGIT antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), ELISA, Immunocytochemistry (ICC), In vivo Studies (in vivo)

Grade: In vivo Grade

Clone: 1F4

Product Details anti-TIGIT Antibody

Expression System: Mammalian cells

Purpose: In vivo Grade Recombinant Anti-mouse TIGIT Monoclonal Antibody (Clone: 1F4), Mouse IgG2a Kappa

Characteristics: The 1F4 antibody binds to the TIGIT protein (WUCAM, Vstm3 or VSIG9), a novel immune checkpoint receptor with inhibitory function. TIGIT is expressed on T cells and natural killer (NK) cells, and several human cancers, including melanoma, NSCLC, and colorectal cancer. Similar to PD-1, the TIGIT receptor limits antitumor immune response in cancer.

Purification: Protein A or G affinity column

Purity: >95 % by reducing SDS-PAGE

Endotoxin Level: < 1 EU per 1 mg of the protein by the LAL method

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: > 3 mg/mL

Storage: 4 °C,-20 °C

Storage Comment: Short time 2 to 8°C as supplied. Long time -20°C to -70°C as supplied.

Target Details for TIGIT

Target: TIGIT (T Cell Immunoreceptor with Ig and ITIM Domains (TIGIT))

Alternative Name: TIGIT

Pathways: Cancer Immune Checkpoints