Recombinant EGFR antibody (AA 1100-1150)
Quick Overview for Recombinant EGFR antibody (AA 1100-1150) (ABIN7795641)
Target
See all EGFR AntibodiesAntibody Type
Reactivity
Host
Clonality
Conjugate
Application
Clone
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Binding Specificity
- AA 1100-1150
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Purpose
- Rabbit anti-EGFR Recombinant Monoclonal Antibody [BLR251L] - BSA-Free
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Purification
- Purified
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Immunogen
- Between 1100 and 1150
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Isotype
- IgG
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1000 μg/mL
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Buffer
- Borate Buffered Saline (BBS) pH 8.2 with 0.09 % Sodium Azide, BSA-Free
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C
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Storage Comment
- 2 - 8 °C
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Expiry Date
- 12 months
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- EGFR (Epidermal Growth Factor Receptor (EGFR))
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Alternative Name
- EGFR
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Background
- The epidermal growth factor receptor (EGFR) is a membrane spanning tyrosine kinase receptor for epidermal growth factor (EGF) and other ligands of the EGF family such as TGF-alpha, amphiregulin, betacellulin, epiregulin and heparin-binding EGF-like growth factor. Upon ligand binding, the EGFR homodimerizes or heterodimerizes with other ErbB receptor family members and tranduces a downstream signal via the ras-raf-mitogen activated protein kinase pathway or the phosphatidylinositol 3-kinase (PI3K)/Akt pathway. Signals from the EGFR function to influence cell proliferation, differentiation, and development.
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Gene ID
- 1956
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UniProt
- P00533
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Pathways
- NF-kappaB Signaling, RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Stem Cell Maintenance, Hepatitis C, Positive Regulation of Response to DNA Damage Stimulus, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, EGFR Downregulation, S100 Proteins
Target
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