Recombinant CTLA4 antibody (C-Term)

Catalog No. ABIN7795649

This Rabbit Monoclonal antibody specifically detects CTLA4 in WB, IHC and mIF. It exhibits reactivity toward Human.

Quick Overview for Recombinant CTLA4 antibody (C-Term) (ABIN7795649)

Target: CTLA4 (Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This CTLA4 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Multiplex Immunofluorescence (mIF)

Clone: BLR257L

Product Details anti-CTLA4 Antibody

Binding Specificity: C-Term

Purpose: Rabbit anti-CTLA4 Recombinant Monoclonal Antibody [BLR257L]

Purification: Purified

Immunogen: Between 173 and C-terminus

Isotype: IgG

Application Details

Application Notes: IHC,1100 to 1500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.,mIF,120 (COMET™),WB,11000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 100 μg/mL

Buffer: Borate Buffered Saline (BBS) pH 8.2 with 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: 2 - 8 °C

Expiry Date: 12 months

Target Details for CTLA4

Target: CTLA4 (Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4))

Alternative Name: CTLA4

Background: CTLA4 is a member of the immunoglobulin superfamily and is an inhibitory receptor acting as a major negative regulator of T-cell responses. The affinity of CTLA4 for its natural B7 family ligands, CD80 and CD86, is considerably stronger than the affinity of their cognate stimulatory coreceptor CD28. [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P16410].

Gene ID: 1493

UniProt: P16410

Pathways: Cancer Immune Checkpoints