Recombinant IFNAR1 antibody (AA 27-436)

Catalog No. ABIN7795661

This Rabbit Monoclonal antibody specifically detects IFNAR1 in WB, IHC, FACS and IP. It exhibits reactivity toward Human.

Quick Overview for Recombinant IFNAR1 antibody (AA 27-436) (ABIN7795661)

Target: IFNAR1 (Interferon alpha/beta Receptor 1 (IFNAR1))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This IFNAR1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunoprecipitation (IP)

Clone: BLR265L

Product Details anti-IFNAR1 Antibody

Binding Specificity: AA 27-436

Purpose: Rabbit anti-Interferon alpha/ beta receptor 1 Recombinant Monoclonal Antibody [BLR265L]

Purification: Purified

Immunogen: Residues 27-436 (ECD)

Isotype: IgG

Application Details

Application Notes: Flow-Cyt,Fixed in 4 % formaldehyde and permeabilized with 90 % methanol. 1 μL per 1 x 10^6 cells.,IHC,11000 to 14000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.,IP,15 μL/mg lysate ,WB,11000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 400 μg/mL

Buffer: Borate Buffered Saline (BBS) pH 8.2 with 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: 2 - 8 °C

Expiry Date: 12 months

Target Details for IFNAR1

Target: IFNAR1 (Interferon alpha/beta Receptor 1 (IFNAR1))

Alternative Name: Interferon alpha/beta receptor 1

Background: Interferon alpha/beta receptor 1 (IFNAR1) associates with IFNAR2 to form the type I interferon receptor. Binding to type I IFNs triggers tyrosine phosphorylation of a number of proteins including JAKs, TYK2, STAT proteins and IFNR alpha- and beta-subunits themselves [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P17181].

Gene ID: 3454

UniProt: P17181

Pathways: JAK-STAT Signaling, Hepatitis C