Recombinant BLM antibody (C-Term)

Catalog No. ABIN7795726

The Rabbit Monoclonal anti-BLM antibody (Clone BLR313M) (ABIN7795726) specifically detects BLM in IHC and ICC. The antibody is reactive with Human and Mouse samples.

Quick Overview for Recombinant BLM antibody (C-Term) (ABIN7795726)

Target: BLM (Bloom Syndrome RecQ Like Helicase (BLM))

Antibody Type: Recombinant Antibody

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Monoclonal

Conjugate: This BLM antibody is un-conjugated

Application: Immunohistochemistry (IHC), Immunocytochemistry (ICC)

Clone: BLR313M

Product Details anti-BLM Antibody

Binding Specificity: C-Term

Purpose: Rabbit anti-BLM Recombinant Monoclonal Antibody [BLR313M]

Purification: Purified

Immunogen: Between 1367 and C-terminus

Isotype: IgG

Application Details

Application Notes: ICC,1100 to 1500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE cell sections.,IHC,1100 to 1500. Epitope retrieval using pressure cooker with citrate buffer pH 6.0 is recommended for FFPE cell sections.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1000 μg/mL

Buffer: Phosphate Buffered Saline (PBS) with 0.09 % Sodium Azide, BSA-Free

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: 2 - 8 °C

Expiry Date: 12 months

Target Details for BLM

Target: BLM (Bloom Syndrome RecQ Like Helicase (BLM))

Alternative Name: BLM

Background: Bloom syndrome protein (BLM) is a RecQ DNA-helicase that plays a role in DNA replication and repair. Mutations and inactivation of BLM result in human syndromes characterized by dwarfism, infertility, erythema, learning disabilities, immune deficiency and predisposition to cancer. BLM has been shown to associate with the BRCA1-associated genome surveillance complex (BASC) which contains BRCA1, MSH2, MSH6, MLH1, ATM, PMS2 and the RAD50-MRE11-NBS1 protein complex.

Gene ID: 641

UniProt: P54132

Pathways: DNA Damage Repair