PALB2
Reactivity: Human
WB, IP
Host: Rabbit
Polyclonal
unconjugated
Application Notes
WB,11,000,IP,6 μL/mg lysate
Restrictions
For Research Use only
Format
Liquid
Concentration
1000 μg/mL
Buffer
Phosphate Buffered Saline (PBS) with 0.09 % Sodium Azide, BSA-Free
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C
Storage Comment
2 - 8 °C
Expiry Date
12 months
Target
PALB2
(Partner and Localizer of BRCA2 (PALB2))
Alternative Name
PALB2
Background
PALB2 (partner and localizer of BRCA2) interacts with BRCA2 and promotes BRCA2 localization and stability. PALB2 is also known as FANCN. Bi-allelic mutations in PALB2 result in Fanconi anemia disorder and breast cancer susceptibility. At the cellular level, PALB2 is important to the DNA damage response and chromosome stability and is essential to BRCA2 function.