Recombinant IFI16 antibody (AA 350-400)

Catalog No. ABIN7795822

The Rabbit Monoclonal anti-IFI16 antibody (Clone BLR375N) (ABIN7795822) specifically detects IFI16 in WB, IHC, IP and ICC. The antibody is reactive with Human samples.

Quick Overview for Recombinant IFI16 antibody (AA 350-400) (ABIN7795822)

Target: IFI16 (Interferon, gamma-Inducible Protein 16 (IFI16))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This IFI16 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunocytochemistry (ICC)

Clone: BLR375N

Product Details anti-IFI16 Antibody

Binding Specificity: AA 350-400

Purpose: Rabbit anti-IFI16 Recombinant Monoclonal Antibody [BLR375N] - BSA-Free

Purification: Purified

Immunogen: between 350 and 400

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1000 μg/mL

Buffer: Phosphate Buffered Saline (PBS) with 0.09 % Sodium Azide, BSA-Free

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: 2 - 8 °C

Expiry Date: 12 months

Target Details for IFI16

Target: IFI16 (Interferon, gamma-Inducible Protein 16 (IFI16))

Alternative Name: IFI16

Background: Gamma-interferon-inducible protein 16 (aka IFI16) is a member of the HIN-200 (hematopoietic interferon-inducible nuclear antigens with 200 amino acid repeats) family of cytokines. IFI16 contains domains involved in DNA binding, transcriptional regulation, and protein-protein interactions and localizes to the nucleoplasm and nucleoli. IFI16 interacts with p53 and retinoblastoma-1, modulates p53 function, and inhibits cell growth in the Ras/Raf signaling pathway. [taken from NCBI Entrez Gene (Gene ID: 3428)].

Gene ID: 3428

UniProt: Q16666

Pathways: Activation of Innate immune Response, Positive Regulation of Endopeptidase Activity, Autophagy, Inflammasome