75 mM PBS, 75 mM NaCl, 0.5 mM EDTA, 0.02 % Sodium azide, 0.1 mM PMSF, pH 7.3
Preservative
Other preservative, PMSF, Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C
Storage Comment
2 - 8 °C
Expiry Date
12 months
Target
APOC3
(Apolipoprotein C-III (APOC3))
Alternative Name
ApoCIII
Background
Apo CIII contains 79 amino acid residues. The m.w. is 8.7 kDa (Brewer et al., 1974). It may inhibit the activation of lipoprotein lipase by apo CIII. Apo CIII is a constituent of both apoB- and apoAI-containing lipoproteins in the circulation. Apo CIII plays a pivotal role in regulating the plasma metabolism of VLDL, IDL, and LDL, primarily by inhibiting receptor-mediated uptake of these lipoproteins by the liver. (Sehayek and Eisenberg 1991, Aalto-Setala et al., 1992, Zheng et al., 2007)