AKR1B1 antibody (AA 151-250) (Biotin)

Catalog No. ABIN739787

The Rabbit Polyclonal anti-AKR1B1 antibody is suitable to detect AKR1B1 in samples from Human, Rat and Mouse. It has been validated for WB, ELISA, IHC (p) and IHC (fro).

Quick Overview for AKR1B1 antibody (AA 151-250) (Biotin) (ABIN739787)

Target: AKR1B1 (Aldo-Keto Reductase Family 1, Member B1 (Aldose Reductase) (AKR1B1))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AKR1B1 antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-AKR1B1 Antibody (Biotin)

Binding Specificity: AA 151-250

Specificity: This antibody may have a secondary cross-reactivity with AKR1C1/2/3/4 due to a 75 % sequence similarity in the corresponding immunogen regions.

Cross-Reactivity: Human, Mouse, Rat

Predicted Reactivity: Dog,Cow,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human AKR1B1

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for AKR1B1

Target: AKR1B1 (Aldo-Keto Reductase Family 1, Member B1 (Aldose Reductase) (AKR1B1))

Alternative Name: AKR1B1

Background:

Synonyms: AR, ADR, ALR2, ALDR1, Aldose reductase, Aldehyde reductase, Aldo-keto reductase family 1 member B1, AKR1B1

Background: Catalyzes the NADPH-dependent reduction of a wide variety of carbonyl-containing compounds to their corresponding alcohols with a broad range of catalytic efficiencies.

Gene ID: 231

UniProt: P15121

Pathways: Metabolism of Steroid Hormones and Vitamin D, C21-Steroid Hormone Metabolic Process, Monocarboxylic Acid Catabolic Process