GRIN1/NMDAR1 antibody (Extracellular, N-Term) (FL550)

Catalog No. ABIN7823555

The Mouse Monoclonal anti-GRIN1/NMDAR1 antibody is suitable to detect GRIN1/NMDAR1 in samples from Rat. It has been validated for IHC and ICC.

Quick Overview for GRIN1/NMDAR1 antibody (Extracellular, N-Term) (FL550) (ABIN7823555)

Target: GRIN1/NMDAR1 (GRIN1) (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 1 (GRIN1))

Reactivity: Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This GRIN1/NMDAR1 antibody is conjugated to FL550

Application: Immunohistochemistry (IHC), Immunocytochemistry (ICC)

Clone: N308-48

Product Details anti-GRIN1/NMDAR1 Antibody (FL550)

Binding Specificity: AA 42-361, Extracellular, N-Term

Purpose: Anti-GluN1/NR1 Glutamate Receptor Antibody FL550 Conjugate

Specificity: No off-targets reported

Cross-Reactivity: Human, Mouse

Characteristics: Our Anti-GluN1/NR1 glutamate receptor mouse monoclonal primary antibody is produced in-house from hybridoma clone N308/48. It detects human, mouse, and rat GluN1/NR1 glutamate receptor, and is purified by protein a chromatography. It is great for use in IHC, ICC.

Purification: Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Purity: Purified mAbs are >90 % specific antibody.

Immunogen: Fusion protein amino acids 42-361 (extracellular N-terminus) of rat NR1 (accession number P35439) produced recombinantly in E. Coli

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: PBS with 0.09 % azide7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: For maximum recovery of product, centrifuge the vial prior to removing the cap.

Storage: 4 °C,-20 °C

Storage Comment: Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C.

Expiry Date: 12 months

Target Details for GRIN1/NMDAR1

Target: GRIN1/NMDAR1 (GRIN1) (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 1 (GRIN1))

Alternative Name: GluN1

Background:

Synonyms: Glutamate receptor ionotropic, NMDA 1 (GluN1) (Glutamate [NMDA] receptor subunit zeta-1) (N-methyl-D-aspartate receptor subunit NR1) (NMD-R1)

Description Logic: Our Anti-GluN1/NR1 glutamate receptor mouse monoclonal primary antibody is produced from hybridoma clone N308/48. It detects human, mouse, and rat GluN1/NR1 glutamate receptor, and is purified by protein a chromatography. It is great for use in IHC, ICC.

Gene Name Alternatives: Grin1 Nmdar1

Molecular Weight: 105 kDa

UniProt: P35439

Pathways: Synaptic Membrane, Feeding Behaviour, Regulation of long-term Neuronal Synaptic Plasticity