KLRC1 antibody (AA 8-100)

Catalog No. ABIN739875

Cited in 2+ publications. The Rabbit Polyclonal anti-KLRC1 antibody (ABIN739875) specifically detects KLRC1 in ELISA, IHC (p), IF (cc), IF (p) and IHC (fro). The antibody is reactive with Mouse and Rat samples.

Quick Overview for KLRC1 antibody (AA 8-100) (ABIN739875)

Target: KLRC1 (Killer Cell Lectin-Like Receptor Subfamily C, Member 1 (KLRC1))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KLRC1 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-KLRC1 Antibody

Binding Specificity: AA 8-100

Cross-Reactivity: Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from mouse NKG2A

Isotype: IgG

Application Details

Application Notes: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-KLRC1 antibody (ABIN739875)

Zou, Zuo, Yang, Fan: "The ANXA1 released from intestinal epithelial cells alleviate DSS-induced colitis by improving NKG2A expression of Natural Killer cells." in: Biochemical and biophysical research communications, Vol. 478, Issue 1, pp. 213-20, (2016) (PubMed).

Hall, Murphy, Quinlan, Hurley, Shanahan, Nally, Melgar: "Natural killer cells protect mice from DSS-induced colitis by regulating neutrophil function via the NKG2A receptor." in: Mucosal immunology, Vol. 6, Issue 5, pp. 1016-26, (2013) (PubMed).

Target Details for KLRC1

Target: KLRC1 (Killer Cell Lectin-Like Receptor Subfamily C, Member 1 (KLRC1))

Alternative Name: NKG2A

Background:

Synonyms: NKG2, NKG2A, CD159A, NKG2-A/NKG2-B type II integral membrane protein, CD159 antigen-like family member A, NK cell receptor A, NKG2-A/B-activating NK receptor, KLRC1

Background: Plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells.

Gene ID: 3821

UniProt: P26715