MPG antibody (AA 101-200) (Biotin)

Catalog No. ABIN739892

The Rabbit Polyclonal anti-MPG antibody has been validated for WB, ELISA, IHC (p) and IHC (fro). It is suitable to detect MPG in samples from Human.

Quick Overview for MPG antibody (AA 101-200) (Biotin) (ABIN739892)

Target: MPG (N-Methylpurine-DNA Glycosylase (MPG))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MPG antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-MPG Antibody (Biotin)

Binding Specificity: AA 101-200

Cross-Reactivity: Human

Predicted Reactivity: Mouse,Rat,Cow,Pig

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human APNG/MPG

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for MPG

Target: MPG (N-Methylpurine-DNA Glycosylase (MPG))

Alternative Name: APNG/MPG

Background:

Synonyms: N-methylpurine-DNA glycosylase isoform a, DNA 3 methyladenine glycosylase, 3 alkyladenine DNA glycosylase, AAG, ADPG, Alkyladenine DNA glycosylase, anpg , APNG, MDG, N methylpurine DNA glycosirase, CRA36.1, MDG, Mid1, PIG11, PIG16, 3MG_HUMAN.

Background: MPG (N-methylpurine DNA glycosylase, or 3-methyladenine (3MeA) DNA glycosylase) repairs the 3MeA lethal lesion blocking DNA replication in Escherichia coli. Analysis of human cDNA libraries found a cDNA that would hybridize to human genomic DNA but not to E. coli or yeast DNA. This MPG gene has been mapped to human chromosome 16 by analysis of a panel of DNAs from mouse/human and hamster/human hybrid cell lines.

Gene ID: 4350

Pathways: DNA Damage Repair