Aprataxin antibody (AA 46-356)

Catalog No. ABIN7825265

The Rabbit Polyclonal anti-Aprataxin antibody (ABIN7825265) specifically detects Aprataxin in ELISA, WB and FACS. The antibody is reactive with Human samples.

Quick Overview for Aprataxin antibody (AA 46-356) (ABIN7825265)

Target: Aprataxin (APTX)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Aprataxin antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Flow Cytometry (FACS)

Product Details anti-Aprataxin Antibody

Binding Specificity: AA 46-356

Purpose: Anti-APTX Antibody

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Human APTXshares 84.8%,80.9% amino acid (aa) sequence identity with mouse,rat APTX,respectively.

Characteristics: Anti-APTX Antibody. Tested in WB, Flow Cytometry, ELISA applications. This antibody reacts with Human.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human APTX recombinant protein (Position: E46-Q356). Human APTXshares 84.8% and 80.9% amino acid (aa) sequence identity with mouse and rat APTX, respectively.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human ELISA, 0.1-0.5 μg/mL

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for Aprataxin

Target: Aprataxin (APTX)

Alternative Name: APTX

Background:

Background: This gene encodes a member of the histidine triad (HIT) superfamily. The encoded protein may play a role in single-stranded DNA repair through its nucleotide-binding activity and its diadenosine polyphosphate hydrolase activity. Mutations in this gene have been associated with ataxia-ocular apraxia. Alternatively spliced transcript variants have been identified for this gene.

Gene Full Name: aprataxin

Molecular Weight: 41 kDa

Gene ID: 54840

UniProt: Q7Z2E3

Pathways: DNA Damage Repair, Chromatin Binding