Epiregulin antibody (AA 24-169)

Catalog No. ABIN7825355

The Rabbit Polyclonal anti-Epiregulin antibody (ABIN7825355) specifically detects Epiregulin in WB, IHC, ELISA and FACS. The antibody is reactive with Human, Rat and Mouse samples.

Quick Overview for Epiregulin antibody (AA 24-169) (ABIN7825355)

Target: Epiregulin (EREG)

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Epiregulin antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS)

Product Details anti-Epiregulin Antibody

Binding Specificity: AA 24-169

Purpose: Anti-EREG Antibody

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Human EREGshares 84.1%,83.4% amino acid (aa) sequence identity with mouse,rat EREG,respectively.

Characteristics: Anti-EREG Antibody. Tested in WB, IHC, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human EREG recombinant protein (Position: F24-V169). Human EREGshares 84.1% and 83.4% amino acid (aa) sequence identity with mouse and rat EREG, respectively.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human ELISA, 0.1-0.5 μg/mL

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for Epiregulin

Target: Epiregulin (EREG)

Alternative Name: EREG

Background:

Background: This gene encodes a secreted peptide hormone and member of the epidermal growth factor (EGF) family of proteins. The encoded protein is a ligand of the epidermal growth factor receptor (EGFR) and the structurally related erb-b2 receptor tyrosine kinase 4 (ERBB4). The encoded protein may be involved in a wide range of biological processes including inflammation, wound healing, oocyte maturation, and cell proliferation. Additionally, the encoded protein may promote the progression of cancers of various human tissues.

Gene Full Name: epiregulin

Molecular Weight: 19 kDa

Gene ID: 2069

UniProt: O14944

Pathways: RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Muscle Cell Differentiation