Fibromodulin antibody (AA 19-376)
Quick Overview for Fibromodulin antibody (AA 19-376) (ABIN7825376)
Target
See all Fibromodulin (FMOD) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 19-376
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Purpose
- Anti-Fibromodulin/FMOD Antibody
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Cross-Reactivity (Details)
- No cross-reactivity with other proteins
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Characteristics
- Anti-Fibromodulin/FMOD Antibody (ABIN7825376). Tested in WB, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.
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Purification
- Immunogen affinity purified.
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Immunogen
- E.coli-derived human Fibromodulin/FMOD recombinant protein (Position: Q19-I376). Human Fibromodulin/FMOD shares 93.3% amino acid (aa) sequence identity with both mouse and rat Fibromodulin/FMOD.
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Isotype
- IgG
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Application Notes
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Western blot, 0.25-0.5 μg/mL, Human, Mouse
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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Concentration
- 500 μg/mL
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Buffer
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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Storage
- 4 °C,-20 °C
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Storage Comment
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- Fibromodulin (FMOD)
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Alternative Name
- FMOD
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Background
- Fibromodulin belongs to the family of small interstitial proteoglycans. The encoded protein possesses a central region containing leucine-rich repeats with 4 keratan sulfate chains, flanked by terminal domains containing disulphide bonds. Owing to the interaction with type I and type II collagen fibrils and in vitro inhibition of fibrillogenesis, the encoded protein may play a role in the assembly of extracellular matrix. It may also regulate TGF-beta activities by sequestering TGF-beta into the extracellular matrix. Sequence variations in this gene may be associated with the pathogenesis of high myopia. Alternative splicing results in multiple transcript variants.
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Molecular Weight
- 60-70 kDa
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Gene ID
- 2331
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UniProt
- Q06828
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Pathways
- Glycosaminoglycan Metabolic Process
Target
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