Hepsin antibody (AA 47-417)

Catalog No. ABIN7825452

This Rabbit Polyclonal antibody specifically detects Hepsin in WB, ELISA, IHC and FACS. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for Hepsin antibody (AA 47-417) (ABIN7825452)

Target: Hepsin (HPN)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Hepsin antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)

Product Details anti-Hepsin Antibody

Binding Specificity: AA 47-417

Purpose: Anti-Hepsin/HPN Antibody

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Human Hepsin,HPNshares 90%,89.2% amino acid (aa) sequence identity with mouse,rat Hepsin,HPN,respectively.

Characteristics: Anti-Hepsin/HPN Antibody. Tested in WB, IHC, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human Hepsin/HPN recombinant protein (Position: D47-L417). Human Hepsin/HPNshares 90% and 89.2% amino acid (aa) sequence identity with mouse and rat Hepsin/HPN, respectively.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human ELISA, 0.1-0.5 μg/mL

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for Hepsin

Target: Hepsin (HPN)

Alternative Name: HPN

Background:

Background: This gene encodes a type II transmembrane serine protease that may be involved in diverse cellular functions, including blood coagulation and the maintenance of cell morphology. Expression of the encoded protein is associated with the growth and progression of cancers, particularly prostate cancer. The protein is cleaved into a catalytic serine protease chain and a non-catalytic scavenger receptor cysteine-rich chain, which associate via a single disulfide bond. Alternative splicing results in multiple transcript variants.

Gene Full Name: hepsin

Molecular Weight: 51 kDa

Gene ID: 3249

UniProt: P05981

Pathways: Regulation of Hormone Metabolic Process, Sensory Perception of Sound