IL-1 beta antibody (AA 1-284)

Catalog No. ABIN7825484

This anti-IL-1 beta antibody is a Rabbit Polyclonal antibody detecting IL-1 beta in IHC. Suitable for Zebrafish (Danio rerio).

Quick Overview for IL-1 beta antibody (AA 1-284) (ABIN7825484)

Target: IL-1 beta (IL1B) (Interleukin 1, beta (IL1B))

Reactivity: Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL-1 beta antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Product Details anti-IL-1 beta Antibody

Binding Specificity: AA 1-284

Purpose: Anti-Zebrafish IL-1 beta/IL1B Antibody

Characteristics: Anti-Zebrafish IL-1 beta/IL1B Antibody catalog #AZA0A8M1PI54. Tested in IHC applications. This antibody reacts with Zebrafish.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived zebrafish IL-1 beta/IL1B recombinant protein (Position: M1-I284)

Isotype: IgG

Application Details

Application Notes: Immunohistochemistry, 2-5 μg/mL, Zebrafish

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Target Details for IL-1 beta

Target: IL-1 beta (IL1B) (Interleukin 1, beta (IL1B))

Alternative Name: IL1B

Background: Interleukin-1 beta(IL-1beta) also know as catabolin, is a cytokine protein that in humans is encoded by the IL1B gene, which localizes to the long arm of chromosome 2 at position 2q13-2q21 between two fragile sites. Interleukin 1(IL-1) is a protein with several biological activities regulating host defense and immune responses. The human IL-1 family plays an important role in the pathogenesis of many diseases and functions as a key mediator of the host response to various infectious, inflammatory, and immunologic challenges.

UniProt: A0A8M154

Pathways: NF-kappaB Signaling, Interferon-gamma Pathway, TLR Signaling, Negative Regulation of Hormone Secretion, Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Glycosaminoglycan Metabolic Process, Myometrial Relaxation and Contraction, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Autophagy, Cancer Immune Checkpoints, Inflammasome