Regulating Synaptic Membrane Exocytosis 1 (RIMS1) (AA 49-1456) antibody

Catalog No. ABIN7825768

The Rabbit Polyclonal anti- antibody has been validated for WB, ELISA and IHC. It is suitable to detect in samples from Rat and Mouse.

Quick Overview for Regulating Synaptic Membrane Exocytosis 1 (RIMS1) (AA 49-1456) antibody (ABIN7825768)

Target: Regulating Synaptic Membrane Exocytosis 1 (RIMS1)

Reactivity: Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details

Binding Specificity: AA 49-1456

Purpose: Anti-RIM1/RIMS1 Antibody

Cross-Reactivity (Details): No cross-reactivity with other proteins

Characteristics: Anti-RIM1/RIMS1 Antibody catalog # A05490. Tested in WB, IHC, ELISA applications. This antibody reacts with Mouse, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human RIM1/RIMS1 recombinant protein (Position: K49-E1456).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Mouse, Rat
Immunohistochemistry, 2-5 μg/mL, Mouse, Rat
ELISA, 0.1-0.5 μg/mL

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Target Details

Target: Regulating Synaptic Membrane Exocytosis 1 (RIMS1)

Alternative Name: RIMS1

Background: The protein encoded by this gene is a RAS gene superfamily member that regulates synaptic vesicle exocytosis. This gene also plays a role in the regulation of voltage-gated calcium channels during neurotransmitter and insulin release. Mutations have suggested a role cognition and have been identified as the cause of cone-rod dystrophy type 7. Multiple transcript variants encoding different isoforms have been described for this gene.

Molecular Weight: 189 kDa

Gene ID: 22999116837

Pathways: Synaptic Membrane, Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport, Regulation of long-term Neuronal Synaptic Plasticity