Recombinant BMP2 antibody

Catalog No. ABIN7828045

This Rabbit Monoclonal antibody specifically detects BMP2 in WB, IHC, ELISA and IF. It exhibits reactivity toward Human, Rat and Mouse.

Quick Overview for Recombinant BMP2 antibody (ABIN7828045)

Target: BMP2 (Bone Morphogenetic Protein 2 (BMP2))

Antibody Type: Recombinant Antibody

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Monoclonal

Conjugate: This BMP2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Clone: A0362R

Product Details anti-BMP2 Antibody

Purpose: Recombinant BMP2 Monoclonal Antibody

Purification: Protein A purified

Immunogen: Recombinant protein corresponding to Mouse BMP2

Isotype: IgG, kappa

Application Details

Application Notes: IHC 1:200-1:1000,WB 1:1000-1:5000,IF 1:200-1:1000,ELISA 1:5000-1:2000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Expiry Date: 12 months

Target Details for BMP2

Target: BMP2 (Bone Morphogenetic Protein 2 (BMP2))

Alternative Name: BMP2

Background: BDA,BMP,BDA2,BMP2A,BMP2,BDA2A,BMP-2,BMP-2A,Bone morphogenetic protein 2,Bone morphogenetic protein 2A,Bmp-2,Bmp2,BDA,BDA2,BMP2A,BMP-2A,Bmp-2,Bmp2,Bone morphogenetic protein-2(BMP-2) is a menmber of the transforming growth factor-beta (TGFB) superfamily. BMP2 is synthesized as a 60 kDa precursor that is processed in the secretory pathway to a small 18 kDa monomer, 2 monomersthen associate to form the active 30 kDa homodimer, which binds to its receptor. There is also a 40-45 kDa form of BMP2, as an amino-teminal propeptide. BMP2 can induce bone formation and regeneration during early embryonic development. It is involved in the hedgehog pathway, TCF beta signaling pathway and cytokine-cytokine receptorinteraction. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Molecular Weight:

Calculated MW: 45, 13 kDa

Observed MW: 30, 13 kDa The actual band is not consistent with the expectation.

UniProt: P12643, P21274, P49001

Pathways: Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Regulation of Muscle Cell Differentiation, Growth Factor Binding, Positive Regulation of fat Cell Differentiation