Recombinant BRD2 antibody (pSer37)

Catalog No. ABIN7828050

The Rabbit Monoclonal anti-BRD2 antibody (Clone A809) (ABIN7828050) specifically detects BRD2 in WB. The antibody is reactive with Human samples.

Quick Overview for Recombinant BRD2 antibody (pSer37) (ABIN7828050)

Target: BRD2 (Bromodomain Containing 2 (BRD2))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This BRD2 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: A809

Product Details anti-BRD2 Antibody

Binding Specificity: pSer37

Purpose: Recombinant Phospho-BRD2 (S37) Monoclonal Antibody

Purification: Protein A purified

Immunogen: Recombinant human BRD2 (phospho S37) fragment

Isotype: IgG, kappa

Application Details

Application Notes: WB 1:4000-1:20000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Expiry Date: 12 months

Target Details for BRD2

Target: BRD2 (Bromodomain Containing 2 (BRD2))

Alternative Name: BRD2

Background: RNF,BRD,FSRG,RING,KIAA,BRD2-IT,BRD2,BRD2-IT1,D6S113E,FSH,FSRG1,NAT,O27.1.1,RING3,RNF3,KIAA9001,Brd2 is a highly conserved member of the BET subfamily of bromodomain proteins that contain two tandem N-terminal bromodomains and a single C-terminal extra-terminal (ET) domain. In addition to its involvement in guiding the expression of cell cycle genes through its binding to multiple E2Fs, Brd2 has been shown to be associated with several regulators of transcription, including TFIID and Swi/Snf complexes. First identified as a nuclear serine/threonine kinase, Brd2, like other bromodomain proteins, is thought to function in mammalian development by regulating chromatin structure and transcription. Brd2 has been shown to bind to histone H4 via acetylated Lys12, a substrate of several histone acetyltransferase transcriptional coactivators. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Molecular Weight:

Calculated MW: 88 kDa

Observed MW: 110 kDa The actual band is not consistent with the expectation.

UniProt: P25440

Pathways: Chromatin Binding, SARS-CoV-2 Protein Interactome, The Global Phosphorylation Landscape of SARS-CoV-2 Infection