Recombinant CSF1R antibody

Catalog No. ABIN7828128

The Rabbit Monoclonal anti-CSF1R antibody (Clone A195) (ABIN7828128) specifically detects CSF1R in IHC. The antibody is reactive with Human and Mouse samples.

Quick Overview for Recombinant CSF1R antibody (ABIN7828128)

Target: CSF1R (Colony Stimulating Factor 1 Receptor (CSF1R))

Antibody Type: Recombinant Antibody

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Monoclonal

Conjugate: This CSF1R antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Clone: A195

Product Details anti-CSF1R Antibody

Purpose: Recombinant CSF-1R Monoclonal Antibody

Purification: Protein A purified

Immunogen: Recombinant human CSF-1R fragment

Isotype: IgG, kappa

Application Details

Application Notes: IHC 1:500-1:2000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Expiry Date: 12 months

Target Details for CSF1R

Target: CSF1R (Colony Stimulating Factor 1 Receptor (CSF1R))

Alternative Name: CSF-1R

Background: FIM,CSF1R,C-FMS,CD115,CSF-1R,CSFR,FIM2,FMS,HDLS,M-CSF-R,BANDDOS,CSF-1 receptor,CSF-1-R,Macrophage colony-stimulating factor 1 receptor,MCSF Receptor,Proto-oncogene c-Fms,M-CSFR,c-fms,CSF-1R,FMS,C FMS,CD 115,CD115 antigen,CFMS,Colony stimulating factor 1 receptor,Colony stimulating factor I receptor,CSF 1 R,CSF 1R,CSF1 R,EC 2.7.10.1,FIM 2,FMS proto oncogene,FMS protooncogene,formerly,Macrophage colony stimulating factor 1 receptor,Macrophage colony stimulating factor I receptor,McDonough feline sarcoma viral (v fms) oncogene homolog,M-CSF Receptor,MCSF Receptor,MCSFR,Oncogen FMS,V-FMS McDonough feline sarcoma viral oncogen homolog,Tyrosine-protein kinase that acts as cell-surface receptor for CSF1 and IL34 and plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines in response to IL34 and CSF1, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone and tooth development. Required for normal male and female fertility, and for normal development of milk ducts and acinar structures in the mammary gland during pregnancy. Promotes reorganization of the actin cytoskeleton, regulates formation of membrane ruffles, cell adhesion and cell migration, and promotes cancer cell invasion. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

UniProt: P07333

Pathways: RTK Signaling, Inositol Metabolic Process, Cell-Cell Junction Organization