Recombinant DBH antibody

Catalog No. ABIN7828162

This Rabbit Monoclonal antibody specifically detects DBH in IHC. It exhibits reactivity toward Human.

Quick Overview for Recombinant DBH antibody (ABIN7828162)

Target: DBH (Dopamine beta-Hydroxylase (Dopamine beta-Monooxygenase) (DBH))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This DBH antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Clone: A691

Product Details anti-DBH Antibody

Purpose: Recombinant Dopamine beta Hydroxylase Monoclonal Antibody

Purification: Protein A purified

Isotype: IgG, kappa

Application Details

Application Notes: IHC 1:50-1:100

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Expiry Date: 12 months

Target Details for DBH

Target: DBH (Dopamine beta-Hydroxylase (Dopamine beta-Monooxygenase) (DBH))

Alternative Name: Dopamine beta Hydroxylase

Background: OTTHUMP,DBH,DBM,Dopamine beta hydroxylase,Dopamine beta monooxygenase,Dopamine beta-hydroxylase (dopamine beta-monooxygenase),Dopamine beta-monooxygenase,DOPO,OTTHUMP00000022501,Soluble dopamine beta-hydroxylase,dopamine beta-hydroxylase,Dopamine β-hydroxylase,Dopamine β-Hydroxylase (DBH) is an enzyme of the copper type II ascorbate-dependent mono-oxygenase family. This enzyme forms homotetramers composed of two noncovalently bound disulfide-linked dimers and is found as both membrane-associated and soluble forms. The soluble form is present in the lumen of secretory granules and is released from cells by exocytosis. DBH converts dopamine to noradrenaline. Deficiency in this enzyme causes a rare disease characterized by a complete absence of noradrenaline and adrenaline in plasma together with increased plasma dopamine levels. Orthostatic hypotension, the main symptom of DBH deficiency, can be alleviated by administration of dihydroxyphenylserine, a synthetic precursor of noradrenaline. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

UniProt: P09172

Pathways: Carbohydrate Homeostasis