Recombinant FADD antibody (pSer194)

Catalog No. ABIN7828195

This Rabbit Monoclonal antibody specifically detects FADD in WB. It exhibits reactivity toward Human.

Quick Overview for Recombinant FADD antibody (pSer194) (ABIN7828195)

Target: FADD (Fas (TNFRSF6)-Associated Via Death Domain (FADD))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This FADD antibody is un-conjugated

Application: Western Blotting (WB)

Clone: A808

Product Details anti-FADD Antibody

Binding Specificity: pSer194

Purpose: Recombinant Phospho-FADD (S194) Monoclonal Antibody

Purification: Protein A purified

Immunogen: Recombinant human FADD (phospho S194) fragment

Isotype: IgG, kappa

Application Details

Application Notes: WB 1:500-1:2000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Expiry Date: 12 months

Target Details for FADD

Target: FADD (Fas (TNFRSF6)-Associated Via Death Domain (FADD))

Alternative Name: FADD

Background: GIG,MORT,FADD,GIG3,MORT1,Fas associated via death domain,FADD protein,Fas (TNFRSF6) associated via death domain,Fas associating death domain containing protein,Fas associating protein,Fas associating protein with death domain,Fas TNFRSF6 associated via death domain,FAS-associated death domain protein,FAS-associating death domain-containing protein,GIG 3,Growth inhibiting gene 3 protein,Growth-inhibiting gene 3 protein,H sapiens mRNA for mediator of receptor induced toxicity,Mediator of receptor induced toxicity,MGC8528,MORT 1,Protein FADD,The protein is an adaptor molecule that interacts with various cell surface receptors and mediates cell apoptotic signals. Through its C-terminal death domain, this protein can be recruited by TNFRSF6/Fas-receptor, tumor necrosis factor receptor, TNFRSF25, and TNFSF10/TRAIL-receptor, and thus it participates in the death signaling initiated by these receptors. Interaction of this protein with the receptors unmasks the N-terminal effector domain of this protein, which allows it to recruit caspase-8, and thereby activate the cysteine protease cascade. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Molecular Weight:

Calculated MW: 23 kDa

Observed MW: 23 kDa

UniProt: Q13158

Pathways: Apoptosis, TLR Signaling, Activation of Innate immune Response, Positive Regulation of Endopeptidase Activity, Toll-Like Receptors Cascades