Recombinant MCM7 antibody

Catalog No. ABIN7828392

The Rabbit Monoclonal anti-MCM7 antibody (Clone A782) (ABIN7828392) specifically detects MCM7 in WB, IF and IP. The antibody is reactive with Human samples.

Quick Overview for Recombinant MCM7 antibody (ABIN7828392)

Target: MCM7 (Minichromosome Maintenance Complex Component 7 (MCM7))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This MCM7 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP)

Clone: A782

Product Details anti-MCM7 Antibody

Purpose: Recombinant MCM7 Monoclonal Antibody

Purification: Protein A purified

Isotype: IgG, kappa

Application Details

Application Notes: WB 1:20000-1:50000,IF 1:100,IP 1:50-1:100

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Expiry Date: 12 months

Target Details for MCM7

Target: MCM7 (Minichromosome Maintenance Complex Component 7 (MCM7))

Alternative Name: MCM7

Background: CDC,PNAS,P1CDC,PPP1R,P1.1-MCM,MCM,MCM7,CDC47,MCM2,P1.1-MCM3,P1CDC47,P85MCM,PNAS146,PPP1R104,formerly,homolog of,regulatory subunit 104,S. cerevisiae,CDABP0042,CDC 47,CDC47 homolog,DNA replication licensing factor MCM7,Homolog of S. cerevisiae Cdc47,MCM 2,MCM 7,MCM7 minichromosome maintenance deficient 7,MCM7_HUMAN,Minichromosome maintainence,Minichromosome Maintainence 7,Minichromosome maintenance complex component 7,Minichromosome maintenance deficient 7,Minichromosome maintenance protein 7,P1.1 MCM3,PNAS 146,Protein phosphatase 1,The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 6 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. Cyclin D1-dependent kinase, CDK4, is found to associate with this protein, and may regulate the binding of this protein with the tumorsuppressor protein RB1/RB. Alternatively spliced transcript variants encoding distinct isoforms have been reported. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Molecular Weight:

Calculated MW: 81 kDa

Observed MW: 81 kDa

UniProt: P33993

Pathways: DNA Damage Repair, Mitotic G1-G1/S Phases, DNA Replication, Chromatin Binding, Synthesis of DNA